Postdoctoral Research Associate (Pharmaceutical Chemistry) | Wissenschaftliche*r Mitarbeiter*in (Postdoktorand*in) Ausschreibungs-ID: fb16-0021-wmz-2025
Philipps-Universität Marburg
Job Summary
This Postdoctoral Research Associate position at Philipps-Universität Marburg offers a unique opportunity to contribute to cutting-edge research in pharmaceutical chemistry, specifically focusing on the design and synthesis of antiviral inhibitors. The successful candidate will engage in computer-based drug design, multi-step organic synthesis of inhibitors for Sudan virus and other Filoviridae, and comprehensive physicochemical and biophysical characterization of these compounds. Key responsibilities include optimizing ligands for ADMET parameters, selecting molecules for hit-to-lead optimization, and preparing compounds for preclinical studies with rigorous quality control. This role is ideal for a highly motivated individual with a strong background in medicinal chemistry, seeking to advance their scientific qualifications within an interdisciplinary project environment.
Required Skills
Education
Completed university degree (Diplom, Master, or equivalent) in Pharmacy or Chemistry with a doctorate (PhD) or proof of a doctoral procedure nearing completion.
Experience
- Several years of experience in the design, synthesis, and characterization of antiviral agents using HPLC, NMR, qNMR, MS, and biophysical methods (e.g., MST, ITC, SPR)
- Relevant experience in fragment optimization via merging, growing, linking, and scaffold-hopping approaches
- Experience in heterocycle synthesis, peptide chemistry, transition metal catalysis, multi-step syntheses, and modern aspects of drug discovery
Languages
Additional
- Fixed-term qualification position until January 31, 2027, subject to funding approval. Opportunity for independent scientific work to further scientific qualification. Willingness for own scientific qualification is expected.
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