PhD Student in Testicular Extracellular Matrix Research | PhD Student (m/w/d)
Universitätsklinikum Münster
Job Summary
This PhD position, embedded within the DFG-funded Collaborative Research Centre 1748 'Principles of Reproduction,' focuses on investigating the role of the testicular extracellular matrix (basement membrane) in influencing Sertoli cell function and spermatogenesis. The successful candidate will develop a gel-based cell culture system for differentiating Sertoli cells, produce recombinant laminin fragments to mimic basement membrane properties, and establish Sertoli cell lines expressing N-cadherin mutants to study cell-cell interactions. Day-to-day tasks involve extensive data collection using techniques like flow cytometry, microscopy, immunoblotting, and transcriptome analysis, followed by comprehensive cell biological and molecular biological data analysis. This role requires a Master’s degree in a relevant life science field, prior experience in protein chemistry and cell biology, and excellent English communication skills, offering a structured, interdisciplinary, and international research environment with competitive compensation.
Required Skills
Education
Master’s degree in biochemistry, biology, pharmacy, and/or chemistry
Experience
- Previous experience with protein chemistry
- Previous experience with cell biology
- Strong interest in research of the extracellular matrix, cell culture systems, and testicular cell differentiation
Languages
Additional
- Fixed-term contract of 3 years; Part-time (65% working hours); Willingness to contribute to an interdisciplinary team; Participation in the Integrated Research Training Group ‘Reproduction.MS PhD-Training Centre in Translational Science’
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