Research Associate (Doctoral Candidate) in Pharmacology | Wissenschaftliche*r Mitarbeiter*in (Doktorand*in) Ausschreibungs-ID: fb16-0032-wmz-2025
Philipps-Universität Marburg
Job Summary
This position is a part-time (65%) Research Associate role, serving as a Doctoral Candidate within the Department of Pharmacy at Philipps University, Marburg, focusing on cutting-edge pharmacological research. The successful candidate will be responsible for developing, cloning, and validating optical G-protein biosensors for use in live cells. Key tasks include planning, executing, and interpreting pharmacological experiments using new optical biosensors in microtiter formats (96/384-well plates), specifically investigating GPCR-dependent conformational changes, interaction profiles of dissociated G-protein subunits, and G-protein-mediated signaling pathways. The role requires a Master's degree in a relevant life science field, practical experience in mammalian cell culture, molecular biology techniques (PCR, cloning), and fluorescence/bioluminescence methods like FRET/BRET. This role offers an excellent opportunity for independent scientific qualification (PhD) supported by university research academies.
Required Skills
Education
Completed scientific university degree (Diploma, Master, or equivalent) in a biological/biochemical, life science, or pharmaceutical discipline
Experience
- Practical experience in cultivating adherent mammalian cells (e.g., HEK-293)
- Practical experience in molecular biological methods for plasmid DNA cloning (PCR, Gibson Assembly, Restriction-Ligation)
- Practical experience in biochemical and/or cell biological methods for researching GPCRs and/or G-proteins in microtiter plate format (96- or 384-Well plates)
- Experience in fluorescence- and/or bioluminescence-based methods including FRET and BRET
Languages
Additional
- Commitment to scientific qualification (e.g., a doctoral project in Pharmacology); Fixed-term contract for 3 years; Part-time position (65% of regular working hours)
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