PhD Researcher in Computational Biology and Systems Immunology | Promotion (m/w/d)

Universitätsklinikum Freiburg

Freiburg im Breisgau, Baden-Württemberg, Deutschland
Published Nov 7, 2025
Full-time
No information

Job Summary

This doctoral position at the University Hospital Freiburg focuses on cutting-edge translational research, investigating the cellular and molecular mechanisms underlying immune evasion in Acute Myeloid Leukemia (AML). The successful candidate will be deeply involved in analyzing and integrating large-scale single-cell and spatial datasets, including advanced platforms like CITE-seq, Spatial Transcriptomics, and CODEX. A core responsibility involves applying modern bioinformatics methodologies, specifically probabilistic and Deep Learning-based models, to identify key cell communication networks and transcriptional programs that facilitate immune escape. This role is ideal for a candidate holding a Master's degree in Bioinformatics, Systems Biology, or a related field, possessing strong proficiency in R/Python and Bash scripting. The position offers close mentorship, integration into the prestigious "OncoEscape" Graduate School, access to high-performance computing resources, and the opportunity to complete a scientific dissertation in Computational Immunology.

Required Skills

Education

Completed Master's degree in Bioinformatics, Systems Biology, Computational Biology, or related scientific field.

Experience

  • Professional experience in analyzing single-cell or omics data (advantageous)
  • Experience with code versioning systems (GitHub/GitLab)
  • Basic knowledge of workflow management systems (e.g., Snakemake)
  • Basic knowledge of High-Performance Computing (HPC) environments
  • Interest in Immuno-oncology, data integration, and translational research

Languages

English (Fluent)

Additional

  • Initial employment contract limited to 24 months (2 years) with the option for extension. Requires commitment to completing a scientific dissertation in Computational Immunology.