PhD Student Position, Translational Cancer Research (Organoid Co-cultures/Microbiome) | PhD Student Position for the DKTK Joint Funding Project "BACTORG: Organoid co-cultures of the Cancer

Job Summary

This PhD position offers an exceptional opportunity to contribute to cutting-edge cancer research at the German Cancer Research Center (DKFZ) by focusing on the 'BACTORG' project. The successful candidate will investigate the profound impact of the intestinal microbiome and its metabolites on colon cancer initiation, progression, and therapeutic response. Day-to-day tasks involve performing state-of-the-art in vitro organoid co-culture and in vivo experiments, utilizing advanced techniques such as single-cell sequencing, CRISPR/Cas9, and various genomics and transcriptomics approaches. A core component of the role is applying advanced bioinformatics platforms to analyze single-cell RNA sequencing datasets and integrate experimental findings with existing clinical and molecular data. We seek highly motivated individuals holding a Master’s degree in fields like Bioinformatics or Molecular Medicine, possessing essential experience in basic molecular biology or proteomics/bioinformatics. This role provides intensive training, access to world-class infrastructure, and collaboration within a diverse, multidisciplinary team of biologists, clinicians, and computational scientists.