Postdoctoral Fellow in Bioinformatics/Computational Biology | Bioinformatiker (m/w/d)

Universitätsklinikum Bonn

Bonn, Nordrhein-Westfalen, Deutschland
Published Oct 22, 2025
Full-time
No information

Job Summary

The University Hospital Bonn (UKB) is seeking a highly motivated Postdoctoral Fellow in Bioinformatics/Computational Biology to join the Clinic for Pediatric Immunology and Rheumatology. This fixed-term position, lasting until September 2032, involves joining a leading interdisciplinary research program focused on uncovering genetic and molecular mechanisms underlying inborn errors of immunity (IEI), autoimmunity, and autoinflammation. The core responsibility is the computational analysis of complex multi-omics datasets, including genomics, transcriptomics, and single-cell/spatial omics, to identify disease pathways and therapeutic targets in pediatric patients. Key tasks include variant interpretation, pathway modeling, and systems immunology integration, requiring close collaboration with wet-lab scientists and clinicians. Candidates must hold a PhD in Bioinformatics or a related field, possess proven experience in multi-omics analysis and Next-Generation Sequencing (NGS), and be proficient in R and command line tools like Python. This role offers integration into the prestigious ImmunoSensation2 Cluster of Excellence and significant opportunities for professional growth in an international research setting.

Required Skills

Education

PhD in Bioinformatics, Computational Biology, Systems Biology, or a related discipline

Experience

  • Proven experience in multi-omics data analysis (WES/WGS, scRNA-seq)
  • Extensive practical experience with Next-Generation Sequencing (NGS)
  • Experience in variant interpretation and statistical genomics
  • Experience in collaborative projects involving patient-derived samples and model organisms
  • Scientific experience in immunology, molecular and cell biology (beneficial)

Languages

English (Fluent)

Additional

  • Fixed-term appointment until 30 September 2032, corresponding to the duration of the professorship.