PhD Student in Cancer Immunotherapy and Tumor Microenvironment Reprogramming | PhD Student in Cancer Immunotherapy and Tumor Microenvironment Reprogramming

Job Summary

This PhD position at the Helmholtz Institute HI-TRON in Mainz focuses on advancing cancer immunotherapies by addressing resistance mechanisms and enhancing anti-tumor immunity. The successful candidate will design and execute combinatorial mRNA delivery strategies to manipulate the tumor microenvironment, aiming to boost immune activation and overcome immunosuppression. Day-to-day tasks involve employing RNA-lipid nanoparticle systems, conducting deep cell phenotyping using advanced techniques like high-parameter flow cytometry and multiplex 3D imaging, and validating therapeutic efficacy with in vitro and ex vivo tumor models. This role offers the opportunity to contribute to cutting-edge translational research, collaborate with international scientific teams, and present findings at conferences, all within a dynamic and supportive research environment dedicated to a life without cancer.