PhD Research Assistant in Functional Cancer Genomics | Biologe (m/w/d)
Philipps-Universität Marburg
Job Summary
This role offers an exciting opportunity for two doctoral researchers to join the Institute for Molecular Oncology at the University of Marburg, working under Prof. Dr. Thorsten Stiewe. The successful candidates will contribute to a DFG-funded project focused on systematically decoding TP53 mutations to advance precision oncology. Day-to-day responsibilities include designing and performing CRISPR-based saturation genome editing, conducting high-throughput functional screens, and utilizing single-cell transcriptomics to analyze variant-specific phenotypes. You will integrate complex datasets to derive mechanistic insights while working toward your doctoral degree. This position is ideal for highly motivated life science graduates eager to work at the intersection of molecular biology, genomics, and bioinformatics. The environment is international and collaborative, providing access to state-of-the-art technologies and support for professional development through the Marburg Research Academy. This is a 3-year, part-time (65%) position starting August 1, 2026, offering a unique opportunity to contribute to high-impact research on one of the most critical cancer-associated genes.
Required Skills
Education
MSc degree (or equivalent) in molecular biology, biochemistry, genetics, or a related life science discipline.
Experience
- Professional experience in mammalian cell culture and advanced molecular cloning techniques
- Practical experience with genome editing technologies such as CRISPR/Cas9
- Experience with next-generation sequencing workflows, including library preparation and data analysis
- Demonstrated experience in handling large-scale datasets and performing data analysis using programming languages like Python
- Evidence of scientific excellence, such as an outstanding MSc thesis, prior research publications, or competitive fellowships
Languages
Additional
- Must be eligible for a doctoral research position under the German Academic Fixed-Term Contract Act (WissZeitVG). Position is part-time (65%).
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