Doctoral Researcher in Cardio-Renal Crosstalk and Systems Biology | PhD student position (f/m/d)

Job Summary

This is a part-time (26 hours/week), four-year limited Doctoral Researcher position focused on investigating heart failure and cardio-renal crosstalk, specifically dissecting platelet-macrophage-fibroblast interaction in chronic kidney disease (CKD)-driven cardiac remodeling. The successful candidate will be rigorously trained in both advanced wet-lab technologies and cutting-edge bioinformatics. Key responsibilities include generating and analyzing state-of-the-art single-cell RNA sequencing and high-resolution spatial transcriptomics datasets (10X Genomics Visium HD and Xenium), performing complex bioinformatic analysis of multi-omic data, and generating human induced pluripotent stem cell (hiPSC) derived cardiac organoids. The role also involves analyzing these organoids using techniques such as immunofluorescent staining, confocal microscopy, and Western blotting. The position is embedded within the DFG SFB/TRR219 Research Training Group, offering comprehensive training, mentoring, and networking events designed to prepare the researcher for a successful career in academia or industry.