PhD Position in Metabolic Microbiome Modeling | PhD position (m/f/d) in „Metabolic microbiome modelling"

Universitätsklinikum Schleswig-Holstein

Kiel, Schleswig-Holstein, Deutschland
Published Dec 5, 2025
Full-time
Permanent

Job Summary

This PhD position focuses on applying systems biological approaches to understand the role of the microbiome in health and disease, specifically utilizing constraint-based metabolic modeling. The successful candidate will integrate large-scale multi-omics data (microbiome, transcriptomic, metabolomic, genomic) to explore metabolic interactions within gut bacterial communities, aiming to uncover unknown cross-feeding interactions in the SIHUMIx model microbiome. This involves building a computational model of SIHUMIx to predict new interactions and community responses to disturbances, with predictions tested experimentally by a partner lab. Candidates should possess a background in bioinformatics, systems biology, or a related field, strong programming skills (R, Python, Linux), and essential experience in metabolic modeling and next-generation sequencing data analysis. This role offers a challenging interdisciplinary research environment within a DFG-funded priority area, providing access to extensive PhD support programs.

Required Skills

Education

PhD student level (or equivalent background)

Experience

  • Background in bioinformatics, systems biology, molecular biology, or a related field
  • Experience in constraint-based metabolic modeling is essential
  • Experience in next-generation sequencing data analysis is essential

Languages

English (Fluent)

Additional

  • Reference number 27635 required for application.