PhD Student Position in Glycobiology of Lymphatic Vessels | PhD student position in Glycobiology of Lymphatic Vessels

Job Summary

The successful candidate will join the Pharmaceutical Immunology group at ETH Zurich for a cutting-edge PhD project focused on the Glycobiology of Lymphatic Vessels. This research aims to understand how specific protein-bound carbohydrates, particularly core-1-derived O-glycans, shape the lymphatic endothelial cell (LEC) glycocalyx and influence its recognition by myeloid immune cells. Day-to-day activities involve working with mice, isolating lymph nodes for primary cell culture and microscopy, and characterizing the LEC glycocalyx using advanced techniques like mass spectrometry and bioinformatics, often in collaboration with international partners at Harvard and Yale. You will investigate underlying mechanisms using FACS, Western blot, and ELISA, and study cell-cell interactions both in vivo and in vitro. This position offers a stimulating, supportive, and international research environment, access to state-of-the-art facilities, and the opportunity to contribute to teaching activities within the group.