PhD Student in CNV-mediated Evolution of Pediatric Brain Tumors | PhD Student in CNV-mediated Evolution of Pediatric Brain Tumors

Deutsches Krebsforschungszentrum

Heidelberg, Neckar, Baden-Württemberg, Deutschland
Published Aug 29, 2025
Full-time
Fixed-term

Job Summary

The German Cancer Research Center is seeking a highly motivated PhD Student to investigate the molecular role of copy-number alterations (CNAs) in the initiation, progression, and evolution of pediatric brain tumors. This role involves utilizing a robust mouse model platform to establish when CNAs arise, identify gene expression, and analyze chromatin accessibility changes in individual tumor cells over time using advanced single-cell sequencing techniques. The project initially focuses on bioinformatic analyses, with opportunities for wet lab work and animal model research at later stages. The successful candidate will contribute to meaningful projects independently within a supportive team, collaborating with other students and postdocs, and leveraging state-of-the-art equipment and international networking opportunities.

Required Skills

Education

Master's or Diploma degree in Biology, Bioinformatics, or a related field

Experience

  • Background knowledge of tumor biology, particularly brain tumors
  • Experience in bioinformatics (beneficial)
  • Experience with molecular biology laboratory methods (beneficial)
  • Willingness to work with animal models (beneficial)

Languages

English (Fluent)

Additional

  • Proof of immunity against measles required (Infection Protection Act (IfSG) regulations)