Postdoctoral Researcher | Postdoc (m/w/d)
Universitätsmedizin Göttingen
Job Summary
This Postdoctoral position at the University Medical Center Göttingen (UMG) offers a compelling opportunity to investigate the molecular pathophysiology of lysosomal and neurodegenerative diseases. The successful candidate will work within the Clinic for Pediatrics and Adolescent Medicine to explore cellular pathologies and develop novel therapeutic strategies. Day-to-day responsibilities include investigating endo-lysosomal trafficking and autophagy, integrating multi-OMICS data (transcriptomics, proteomics, metabolomics), and validating therapeutic targets using CRISPR/Cas9 and pharmacological perturbations. The role involves maintaining patient-derived cell models and automating high-throughput assays for drug repurposing. This position is particularly attractive for researchers seeking a highly translational environment that bridges fundamental biology with direct patient-oriented impact. Joining one of the region's largest employers, the researcher will benefit from an extensive scientific network including the DZKJ and Fraunhofer ITMP, fostering significant professional growth in a collaborative neuroscience setting.
Required Skills
Education
PhD (completed or near completion) in Life Sciences, Biology, Molecular Medicine, Biochemistry, or a related discipline.
Experience
- Professional experience in molecular and cell biology research
- Experience in investigating molecular mechanisms such as endo-lysosomal trafficking or autophagy
- Demonstrated experience in target validation using genetic or pharmacological perturbations
- Experience in maintaining and characterizing patient-derived cell models (fibroblasts/iPSCs)
- Experience in documenting, presenting, and publishing scientific results in a peer-reviewed context
Languages
Additional
- This is a full-time position limited to a duration of 3 years. Candidates must demonstrate high self-motivation and an independent, creative working style within a collaborative team environment.
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