Experimental Biologist (RNA Therapeutics) | Biologist (m/w/d)

Job Summary

This role seeks an experimental biologist to drive the development of next-generation RNA-based precision therapies within the curATime initiative, focusing on cardiovascular medicine. The successful candidate will be based at TRON in the Department for Cardiovascular Therapeutics and will be responsible for the functional characterization of novel programmable RNA switches (eToeholds) using cell-free systems, in vitro models, and cardiovascular disease models, including mouse models of atherothrombosis and myocardial infarction. Key daily tasks involve designing and executing reporter assays, LNP-based mRNA transfection, flow cytometry, microscopy, and tissue/expression analyses. This is a highly collaborative position requiring close interaction with a computational biologist to iteratively refine RNA structure designs based on experimental results, driving therapeutic translation. A PhD in molecular biology or a related field, coupled with strong hands-on experience in RNA-based work and cell culture, is essential for success in this cutting-edge translational research environment.