Postdoctoral Fellow in Bioinformatics (Genomic Data Analysis) | Bioinformatiker (m/w/d)
Institute of Cardiovascular Regeneration
Job Summary
The Goethe University Frankfurt is seeking a highly motivated Postdoctoral Fellow to join the Institute of Cardiovascular Regeneration. This role focuses on analyzing large-scale human genomic and transcriptomic data, specifically whole exome sequencing (WES), variant discovery, and integrative analyses with clinical phenotypes to understand immune dysregulation in cardiovascular health. Day-to-day tasks involve building and maintaining robust WES pipelines, performing germline variant calling and association tests, and developing/extending analysis workflows using tools like Nextflow or Snakemake. The successful candidate will integrate WES results with multi-omics data (RNA-seq, ATAC-seq) and clinical endpoints, ensuring rigorous statistics and version control. This position offers a stimulating, international, and collaborative environment with flexible scheduling, excellent mentoring, and the opportunity to drive independent projects and publish high-impact research.
Required Skills
Education
Doctorate (PhD) in Computational Biology, Bioinformatics, Biostatistics, Computer Science, or a related discipline
Experience
- Doctorate in computational biology, bioinformatics, biostatistics, computer science, or a related discipline
- Hands-on experience with WES/whole-genome variant discovery and downstream analysis
- Experience with tools like BWA/Minimap2, GATK, DeepVariant, and bcftools
- Professional experience with Python and/or R for data analysis
- Experience collaborating with clinicians (plus)
Languages
Additional
- Landesticket Hessen for free public transportation within Hesse
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