Scientist, Protein Conjugate Chemistry | Biochemiker (m/w/d)

Ascendis Pharma GmbH

Heidelberg, Neckar, Baden-Württemberg, Deutschland
Published Oct 29, 2025
Full-time
No information

Job Summary

Ascendis Pharma is seeking a highly motivated Associate Scientist (M.Sc.) or Scientist (Ph.D.) to join the Protein Chemistry team, focusing on the design, synthesis, and comprehensive characterization of therapeutic protein conjugates. Day-to-day responsibilities include optimizing purification workflows, developing advanced chromatographic and mass spectrometric techniques, and assessing innovative technologies to enhance platform capabilities. The role requires a strong theoretical foundation and hands-on expertise in protein chemistry, bioconjugation, and analytical methods (e.g., SEC, HPLC, TFF), coupled with proficiency in operating specialized chromatography systems like Äkta and Agilent. The ideal candidate possesses a proactive, creative, and collaborative mindset, thriving in a dynamic, team-oriented environment focused on open communication and knowledge sharing. This position is attractive for scientists passionate about tackling complex scientific challenges and directly contributing to the development of innovative, life-changing therapies.

Required Skills

Education

Master’s degree (Associate Scientist) or Doctoral degree (Scientist) in Biochemistry or a closely related field

Experience

  • Hands-on expertise in protein chemistry and analytical techniques, including bioconjugation
  • Professional experience operating Äkta and Agilent chromatography systems
  • Proven creativity in developing synthetic strategies for complex protein conjugates
  • Experience supporting pre-clinical in vitro and in vivo studies

Languages

German (Intermediate)English (Fluent)

Additional

  • Independent, well-organized, and methodical approach to work