Scientist, Protein Sciences (Biochemistry/Biotechnology) | Biochemiker (m/w/d)

Ascendis Pharma GmbH

Heidelberg, Neckar, Baden-Württemberg, Deutschland
Published Oct 29, 2025
Full-time
No information

Job Summary

This role is for a highly motivated Associate Scientist (M.Sc.) or Scientist (Ph.D.) to join the Protein Sciences group, focusing on the production and characterization of therapeutic protein candidates for pre-clinical testing. Day-to-day responsibilities include developing and optimizing protein production processes, encompassing molecular cloning, expression, and purification, and performing rigorous quality characterization using analytical techniques like ÄKTA/HPLC, SEC, and RP-HPLC. The ideal candidate possesses strong hands-on expertise in protein purification, downstream process development, and experience with mammalian expression systems (HEK293, CHO). Success requires scientific creativity, analytical rigor, excellent English communication skills, and a collaborative spirit to contribute innovative concepts and documentation (SOPs, reports) within multidisciplinary project teams, ultimately helping develop novel, life-improving drugs.

Required Skills

Education

Master’s degree (Associate Scientist) or Ph.D. (Scientist) in Biochemistry, Biotechnology, or a related field

Experience

  • Strong hands-on experience in protein purification and analytical techniques (ÄKTA/HPLC)
  • Deep knowledge of chromatography and downstream process development
  • Professional experience in protein characterization (e.g., SEC, RP-HPLC)
  • Experience in mammalian protein expression systems (e.g., HEK293, CHO)

Languages

German (Intermediate)English (Fluent)

Additional

  • Structured, detail-oriented working style; High motivation and flexibility to support therapeutic protein development; Strong problem-solving skills and conceptual thinking