Research Scientist Computational Structural Biology | Wissenschaftliche Mitarbeiterin / Wissenschaftlicher Mitarbeiter Computational Structural Biology
Robert Koch-Institut
Job Summary
This role involves developing and establishing novel AI-based procedures for targeted protein design within the Center for Biological Hazards and Special Pathogens (ZBS) at the Robert Koch Institute (RKI). The successful candidate will focus on developing, validating, and establishing Proteomics-based detection methods, particularly utilizing Mass Spectrometry (MS) for the detection of high-molecular agents. A key responsibility is establishing Machine Learning (ML) methods for the precise MS-based detection of bioterrorism-relevant protein structures, including modeling antibody-antigen interactions. This position requires strong expertise in Computational Structural Biology, protein structure elucidation tools, and collaboration with national security authorities. The ideal candidate holds a PhD in a relevant scientific discipline and possesses advanced proficiency in both German and English, contributing actively to public health security in Germany.
Required Skills
Education
University Diploma or Master's degree in Biology, Chemistry, Biotechnology, or comparable discipline; Doctoral degree (PhD)
Experience
- Professional experience in Protein Structural Biology
- Experience in applying programs and tools for protein structure elucidation
- Experience in the technical/scientific field related to Protein Structural Biology and/or Proteomics
- Experience applying Machine Learning methods in Structural Biology (Computational Structural Biology)
- Willingness to participate in the ZBS on-call service
Languages
Additional
- Positive completion of an extended security clearance check according to § 9 of the Security Clearance Act (SÜG); Contract duration is fixed-term.
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