Doctoral Researcher in Proteomics and BMP Signal Transduction | Graduate Student in Proteomics and BMP Signal Transduction

Deutsches Krebsforschungszentrum

Heidelberg, Neckar, Baden-Württemberg, Deutschland
Published Aug 6, 2025
Full-time
Fixed-term

Job Summary

The German Cancer Research Center is seeking a highly motivated Doctoral Researcher to join the "Systems Biology of Signal Transduction" division, starting October 2025. This role focuses on investigating BMP receptor complex composition and iron-induced signal transduction, particularly in hepatocytes and hepatocellular carcinoma cells. The successful candidate will develop and apply quantitative mass spectrometry methods for various biological samples, integrate proteomics data with mathematical models to understand iron-regulatory pathways, and utilize phosphoproteomics to explore liver-bone communication. This interdisciplinary position involves close collaboration with computational biologists, modelers, and clinicians, contributing to publications and scientific presentations. It's an excellent opportunity for a talented individual to contribute to cutting-edge cancer research within a supportive and collaborative environment.

Required Skills

Education

Master's degree in Biochemistry, Systems Biology, or a related life science discipline

Experience

  • Expertise in cell biology, signal transduction, and iron metabolism
  • Expertise in mass spectrometry-based proteomics (sample preparation, acquisition, data interpretation)
  • Experience in handling complex omics datasets
  • Experience in applying statistical and computational tools (R, Python) for data analysis is advantageous
  • Familiarity with mathematical modeling in systems biology and pathway-level data integration is advantageous
  • Strong scientific track record demonstrated by publications in peer-reviewed journals

Languages

English (Fluent)

Additional

  • Proof of immunity against measles is required due to the Infection Protection Act (IfSG).