PhD Student in Molecular Mechanisms of Metronidazole Resistance in Bacteroides fragilis | Doktorand/in PhD (m/w/d) „Molekulare Mechanismen der Metronidazol-Resistenz bei Bacteroides fragilis
Deutsche Sammlung von Mikrooganismen und Zellkulturen (DSMZ)
Job Summary
This PhD position offers a unique opportunity to conduct cutting-edge research at the Leibniz Institute DSMZ in Braunschweig, focusing on the molecular mechanisms of antibiotic resistance in the human pathobiont Bacteroides fragilis. The successful candidate will investigate resistance to metronidazole by characterizing metabolic adaptations in clinical isolates and elucidating the roles of Nim proteins and key metabolic enzymes. Working in collaboration with a partner PhD student at the Medical University of Vienna, you will utilize advanced technologies including long-read DNA sequencing, metabolomics, and high-performance computing clusters. This role is ideal for a dedicated researcher looking to identify diagnostic markers and deepen the global understanding of clinical resistance mechanisms. The position is a 65% part-time role for three years, offering a supportive environment with professional mentoring and flexible work-life balance through the 'berufundfamilie' certification.
Required Skills
Education
Master's degree in Life Sciences or a related field. For degrees obtained outside of Germany, proof of equivalence (ZAB) is required.
Experience
- Professional experience in microbiological and molecular biological methods is advantageous
- Experience in interdisciplinary scientific work and collaborative research
- Experience with metabolic characterization or enzyme analysis is preferred
Languages
Additional
- The position is a fixed-term contract for 3 years at 65% part-time (TV-L 13). Applicants must provide contact details for two academic references. Application deadline is May 11, 2026.