Master Chemist in Chemistry R&D Diagnostics with Focus on Oligonucleotide Synthesis | Master Chemistry (m/f/d) in Chemistry R&D Diagnostics with focus on Oligonucleotide synthesis

Roche Diagnostics GmbH

Penzberg, Bayern, Deutschland
Published Jul 7, 2025
Full-time
Fixed-term

Job Summary

Join a dynamic R&D team at Roche, where you'll be instrumental in developing innovative chemical assay components for diagnostics and pharmaceuticals. This role involves hands-on chemical synthesis, specifically focusing on challenging nucleotides and their conjugates. You will be responsible for the entire process, from synthesis and purification using techniques like RP-HPLC and IEX, to characterization with methods such as HPLC, LC-MS, UV-Vis, and NMR. A key aspect of your work will be optimizing and scaling established synthetic processes for production transfer, all while strictly adhering to safety, environmental, and quality guidelines. This is an exciting opportunity for an expert in preparative organic and oligonucleotide synthesis to contribute to life-changing healthcare solutions.

Required Skills

Education

Master’s degree in Chemistry

Experience

  • At least 3 years of specialized knowledge in preparative organic synthesis and oligonucleotide synthesis
  • Experience with purification of synthesis products
  • Experience with non-standard nucleotide building blocks
  • Experience with large-scale, high-quality nucleotide synthesis

Languages

German (Fluent)English (Fluent)

Additional

  • This is a fixed-term position for 2 years.