Senior Principal Scientist siRNA | Senior Principal Scientist siRNA (m/f/d)
Bayer AG Pharmaceuticals
Job Summary
This is a key scientific leadership role focused on advancing targeted siRNA-based medicines from early research through clinical candidate selection. The Senior Principal Scientist will act as the primary subject matter expert on siRNA therapeutics, providing enterprise-level scientific guidance on design, delivery, and best practices across R&D teams. Day-to-day responsibilities involve steering complex studies, managing external collaborations (CROs/partners), leading interdisciplinary matrix teams, and initiating novel research in siRNA and tissue targeting. The ideal candidate requires a Ph.D. in a relevant life science field, significant post-doctoral or industry experience in siRNA drug discovery, and a proven track record of translating cutting-edge science into therapeutic opportunities. This position is attractive as it offers the chance to drive innovation, mentor junior scientists, and shape the strategic direction of a major pharmaceutical company's targeted RNA therapeutics portfolio.
Required Skills
Education
Ph.D. in Biochemistry, Chemistry, Molecular Biology, Pharmacology, or a related field
Experience
- Significant experience in post-doctoral or industry setting in drug discovery, with a strong focus on siRNA research
- Professional experience designing siRNA molecules and optimizing delivery methods
- Proven track record in targeted siRNA related drug discovery or development from ideation to preclinical candidate selection
- Experience in taking scientific ideas from concept to validation
- Mentorship experience is valued
- Experience in evaluating project success and making data-driven recommendations
Languages
Additional
- Must demonstrate Visionary, Architect, Coach, and Catalyst leadership behaviors; Must possess a drug-hunter mindset; Location constraint: Wuppertal-Aprath, Germany.
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