Senior Scientist | Biologe (m/w/d)

AaviGen GmbH

Heidelberg, Neckar, Baden-Württemberg, Deutschland
Published Dec 18, 2025
Full-time
No information

Job Summary

AaviGen, a cutting-edge preclinical biotech company developing innovative gene therapies using heart-specific AAV vectors for cardiovascular and cardiopulmonary diseases, seeks a Senior Scientist to join their dynamic research team. This pivotal role involves actively shaping the development of the lead program by independently conceiving, executing, and evaluating experiments assessing the molecular cardiac function of the product in preclinical in vitro and in vivo models. Key responsibilities include planning and conducting complex heart function studies, such as Excitation-Contraction Coupling and Ca++ Cycling measurements, alongside applying complementary molecular biology techniques like dPCR, Western Blot, and ELISA. The role requires meticulous data analysis, documentation, and presentation, as well as coordinating research and analyzing data obtained from external partners (e.g., Ultrasound and MRI). Candidates must possess deep expertise in cardiac physiology and relevant practical experience in advanced cardiac models or imaging techniques.

Required Skills

Education

Master's degree or PhD in Biosciences (Molecular Biology, Biotechnology, Biochemistry, or related field)

Experience

  • 5+ years of professional experience with a Master's degree, or a completed PhD, in Biosciences (e.g., Molecular Biology, Biotechnology, Biochemistry) or a related field
  • Relevant practical experience in cardiac physiology, with a deep understanding of functions like Excitation-Contraction Coupling and Ca++ Cycling
  • Practical experience in at least one of the following areas: artificial 3D cardiac cell cultures (Engineered Heart Tissues or Organoids), hiPSC-derived cardiomyocytes, Ultrasound imaging, P/V-Loops, in vitro measurement of calcium transients/contraction forces, or working with in vivo/in vitro HFrEF or HFpEF models
  • Structured, project-oriented work style with a hands-on mentality

Languages

German (Fluent)English (Fluent)

Additional

  • Not specified