Research Associate (Postdoctoral Researcher) in Biochemistry and Bacterial Cell Biology | Wissenschaftliche*r Mitarbeiter*in (Postdoktorand*in) Ausschreibungs-ID: ZE-0106-synmikro-wmz-2025
Philipps-Universität Marburg
Job Summary
This Postdoctoral Research Associate position at the Center for Synthetic Microbiology (SYNMIKRO) focuses on the ERC Advanced Grant “C-SWITCH,” investigating a novel class of nucleotide-dependent molecular switches that utilize the pyrimidine nucleotide CTP. The researcher will conduct biochemical, biophysical, and structural biology analyses of C-SWITCH candidates, functionally characterizing proteins both in vitro and in vivo using genetic, cell biological, and physiological approaches. A key objective is to understand how these regulators control protein activity and cellular functions, potentially identifying new targets for antibacterial therapies to combat antibiotic resistance. The ideal candidate holds a PhD in a relevant field (Biochemistry, Microbiology, or Cell Biology) and possesses extensive experience in protein purification, in vitro characterization, and standard molecular biology techniques. This role offers the opportunity to contribute to cutting-edge, multidisciplinary, and international research within a leading European microbiological research center, disseminating findings through publications and conference presentations.
Required Skills
Education
Completed university degree (Diploma, Master, or equivalent) and a PhD in a relevant area (e.g., Biochemistry, Microbiology, or Cell Biology)
Experience
- Comprehensive experience in the purification and in vitro characterization of proteins
- Expertise in all common molecular biology methods
- Experience in the development and guidance of scientific projects
- Expertise in the use of biological and structural biology standard software and online resources
Languages
Additional
- Fixed-term contract until September 30, 2028; Must be eligible for temporary project employment outside of the standard German academic fixed-term contract law (§ 2, 1 WissZeitVG).
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